Effect of clavulanic acid on the activities of ten beta-lactam agents against members of the Bacteroides fragilis group
Open Access
- 1 May 1984
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 25 (5) , 662-665
- https://doi.org/10.1128/aac.25.5.662
Abstract
Clavulanic acid reduced the MICs of amoxicillin, carbencillin , cefamandole, cefotaxime, ceftazidime, ceftizoxime, cephalothin, and penicillin G, but not of cefoxitin or moxalactam, against 77 isolates of the Bacteroides fragilis group, all rapidly beta-lactamase positive by the nitrocefin slide test. It had no effect on the susceptibilities of eight Bacteroides distasonis strains that were slowly beta-lactamase positive (18 h of incubation).Keywords
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