Long duration of septicaemic salmonellosis: 35 cases with 12 implicated species of salmonella

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Abstract
Thirty five cases of prolonged septicemic'' salmonellosis were described in Minas Gerais, Brazil. This salmonellosis does not represent a prolonged course of classical typhoid fever, but exhibits a clinical picture of a reticulo-endotheliosis closely related to that of kala-azar. Prolonged septicemia is 1 of the most constant characteristics of the disease, and differs from those severe and lethal, as well as from the benign ambulatory, types observed in typhoid fever. The following salmonellae were implicated by serological typing of blood culture: Salmonella typhi, S. newport, S. panama, S. dublin, S. anatum, S. paratyphi,A, S. paratyphi C, S. cholerae-suis, S. cholerae-suis var. kunzendorf, S. derby and S. montevideo. There is evidence that biochemical identification of salmonellae and routine Widal agglutination tests were not suitable laboratory procedures for definite identification. The patients showed dramatic clinical response to Chloromycetin [chloramphenicol], without relapses. Schistosoma mansoni infection was constant in these cases, but there is no proof of its role in the pathogenesis of septicemic salmonellosis of protracted course.