Frailty Thy Name Is ... Phrailty?
Open Access
- 1 July 2007
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journals of Gerontology: Series A
- Vol. 62 (7) , 728-730
- https://doi.org/10.1093/gerona/62.7.728
Abstract
THE precise characterization of frailty as a state of physiologic vulnerability has been extremely useful for research (1,2). In particular, the frailty index first validated in the Cardiovascular Health Study (CHS) is a reliable predictor of adverse outcomes and a valuable and versatile tool (3–7). In contrast, conceptualizing frailty as physiologic vulnerability can be problematic, partly because clinicians typically apply the word “frail” to functionally limited or even overtly disabled elders who are suffering the cumulative effects of disease-related, psychosocial, and environmental challenges (8–13). Thus, the research definition creates cognitive dissonance because it does not fully equate to what many physicians have in mind when they envision a frail elder (Figure 1).This publication has 18 references indexed in Scilit:
- A search for principles of disability using experimental impairment of Drosophila melanogasterExperimental Gerontology, 2007
- Vitamin and Carotenoid Status in Older Women: Associations With the Frailty SyndromeThe Journals of Gerontology: Series A, 2006
- What would make a definition of frailty successful?Age and Ageing, 2005
- From Bedside to Bench: Research Agenda for FrailtyScience of Aging Knowledge Environment, 2005
- Frailty and Its Definition: A Worthy ChallengeJournal of the American Geriatrics Society, 2005
- Designing Randomized, Controlled Trials Aimed at Preventing or Delaying Functional Decline and Disability in Frail, Older Persons: A Consensus ReportJournal of the American Geriatrics Society, 2004
- Untangling the Concepts of Disability, Frailty, and Comorbidity: Implications for Improved Targeting and CareThe Journals of Gerontology: Series A, 2004
- Frailty in Older Adults: Evidence for a PhenotypeThe Journals of Gerontology: Series A, 2001
- Toward an Understanding of FrailtyAnnals of Internal Medicine, 1999
- The disablement processSocial Science & Medicine, 1994