THE MDG1 REGION CONTAINS TRANSCRIPTION TERMINATION SITES

  • 1 November 1990
    • journal article
    • research article
    • Vol. 26  (11) , 1893-1904
Abstract
The analysis of MDG1 transcription in Drosophila melanogaster cells discovered transcription termination sites in the leader region of the element. These termination sites are localized 1 kb downstream the transcription initiation site and contain long oligo(dA) blocks. The transcription termination is regulated in different cell types. The transient expression of the deletion mutants has shown that a small ORF in the MDG leader region can be translated. This points on possible transcription reiniatition during the process of reading the main ORF MDG1.