The immune respone of plaice (Pleuronectes platessaL.) to the metacercariae ofCryptocotyle linguaandRhipidocoytle johnstonei

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Abstract
The humoral immune response of plaice to infestations of selected metacercariae was studied. Precipitating antibodies to both Cryptocotyle lingua and Rhipidocotyle johnstonei were demonstrated using agar geldiffusion techniques. Immunochemical investigations of these antibodies indicated they were macroglobulins, resembling immunaglobulin M(IgM) of mammals. The rate and magnitude of antibody production by the host was determined by the ambient temperature