Treatment of Trichinosis With Thiabendazole
- 30 November 1964
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 190 (9) , 852-853
- https://doi.org/10.1001/jama.1964.03070220058021
Abstract
THE PURPOSE of this preliminary report is to describe our observations on the use of thiabendazole (2-[4′-thiazolyl]-benzimidazole) in the treatment of trichinosis in humans. Extensive and well-documented animal experiments have indicated that the drug is rapidly absorbed and excreted in animals, that it has broad antihelminthic activity, and that toxicity is minimal.1At the time the drug was used by us it had been administered, usually for one or two days, to approximately 4,000 humans for various helminthic infections. A case report on its use in the treatment of trichinosis was published inThe Journalsome months ago under the title "Thiabendazole: Probable Cure for Trichinosis."2 Case Information On March 3, 1964, 11 executives of a major business organization had dinner in a restaurant. Within the next two to four weeks, six of these executives developed trichinosis and two others had some evidence of this disease. In addition, theKeywords
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