STUDIES ON THE PHYSIOLOGY OF HUNGER. I. THE EFFECT OF INTRAVENOUS ADMINISTRATION OF GLUCOSE ON GASTRIC HUNGER CONTRACTIONS IN MAN 1

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Abstract
In one half of a series of 40 adult human subjects intravenous administration of 50 ml of a 50% solution of glucose was followed within 5 minutes by cessation of gastric hunger contractions. At 10 and 20 minutes following injection the peripheral capillary-venous glucose differences of the sugjects whose contractions were inhibited were significantly higher than those whose contractions persisted. It is concluded that metabolic events accompanying increased peripheral removal of glucose from the blood have an inhibiting effect on gastric hunger contractions.