Quantitative Relations Between the Oral and Intravenous Glucose Tolerance Curves

Abstract
An expression is derived for the oral glucose tolerance curve, as a reflection of the net balance between over-all glucose removal rate and intestinal absorption rate. Use of this expression suggested that the removal rate for orally administered glucose was approximately 3 times as high as for intravenously administered glucose, a difference which may be the result of a higher liver uptake of glucose following oral administration. Liver glycogenesis could not account for the difference.

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