Prevention of Pyelonephritis By Immunization With P-Fimbriae
- 1 March 1984
- journal article
- research article
- Published by Wolters Kluwer Health in Journal of Urology
- Vol. 131 (3) , 602-607
- https://doi.org/10.1016/s0022-5347(17)50513-3
Abstract
[Pyelonephritic D-mannose resistant] P-fimbriae is a virulence factor in human and nonhuman primate urinary tract infections caused by Escherichia coli, because of bacterial adherence to urothelial cells which is mediated by adherence of fimbriae to a specific glycolipid receptor on the cell membrane of these cells. P-fimbriae was purified for immunization of monkeys [Macaca fascicularis]. High titers of antifimbrial antibody protected against acute and chronic pyelonephritis after renal inoculations of P-fimbriated E. coli.This publication has 18 references indexed in Scilit:
- Receptors for Pyelonephritogenic Escherichia Coli in PrimatesJournal of Urology, 1984
- P-fimbriae of pyelonephritogenic escherichia coli: Significance for reflux and renal scarring — A hypothesisInfection, 1983
- Clinical Pyelonephritis and Focal Renal Scarring: A Selected Review of Pathogenesis, Prevention, and PrognosisPediatric Clinics of North America, 1982
- OCCURRENCE OF P-FIMBRIATED ESCHERICHIA COLI IN URINARY TRACT INFECTIONSThe Lancet, 1981
- THE PkANTIGEN AS RECEPTOR FOR THE HAEMAGGLUTININ OF PYELONEPHRITICESCHERICHIA COLIFEMS Microbiology Letters, 1980
- Antipili antibody affords protection against experimental ascending pyelonephritis.Journal of Clinical Investigation, 1979
- BACTERIAL ADHERENCE TO PERIURETHRAL EPITHELIAL CELLS IN GIRLS PRONE TO URINARY-TRACT INFECTIONSThe Lancet, 1978
- Type I Escherichia coli pili: characterization of binding to monkey kidney cells.The Journal of Experimental Medicine, 1977
- VARIABLE ADHERENCE TO NORMAL HUMAN URINARY-TRACT EPITHELIAL CELLS OF ESCHERICHIA COLI STRAINS ASSOCIATED WITH VARIOUS FORMS OF URINARY-TRACT INFECTIONThe Lancet, 1976
- Observations On The Pathogenic Properties Of The K88, Hly And Ent Plasmids Of Escherichia Coli With Particular Reference To Porcine DiarrhoeaJournal of Medical Microbiology, 1971