Radiation effects in the canine brain evaluated by quantitative computed tomography.

Abstract
Quantitative computed tomography (QCT) and histopathology were used to assess the effects of large single doses of X-irradiation on the normal canine brain. Measurable changes demonstrated by QCT included increased contrast enhancement and enlargement of the lateral ventricles, which were observed prior to any clinical signs. QCT methods apparently are effective in the noninvasive evaluation of radiation-induced brain injury [sometimes caused during the radiotherapy of human intracranial neoplasia].