The effect of culture conditions and toxicity on the ames salmonella/microsome agar incorporation mutagenicity assay
- 1 January 1983
- journal article
- research article
- Published by Wiley in Environmental Mutagenesis
- Vol. 5 (4) , 541-551
- https://doi.org/10.1002/em.2860050404
Abstract
Various methods were used to reconstruct an environment similar to a chemically bactericidal or bacteriostatic effect in the Ames mutagenicity assay in order to determine whether a false‐positive result could occur. Neither population reduction, sonication, nor increased histidine produced an increase of spurious revertant colonies.Keywords
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