A class of highly polymorphic tetranucleotide repeats for canine genetic mapping
- 1 May 1996
- journal article
- research article
- Published by Springer Nature in Mammalian Genome
- Vol. 7 (5) , 359-362
- https://doi.org/10.1007/s003359900104
Abstract
We have identified and characterized a new class of polymorphic markers for the canine genome from a simple tetranucleotide repeat sequence, (GAAA)n. Genetic markers derived from this repeat are highly polymorphic compared with other canine microsatellites, yet are stable enough to be useful for following Mendelian inheritance in multigeneration pedigrees. We show further that (GAAA)n repeats are distributed throughout the canine genome and occur with sufficient frequency to be useful in the development of a framework map of the canine genome.Keywords
This publication has 25 references indexed in Scilit:
- A Comprehensive Human Linkage Map with Centimorgan DensityScience, 1994
- A genetic linkage map of the bovine genomeNature Genetics, 1994
- Mutation of human short tandem repeatsHuman Molecular Genetics, 1993
- Isolation and characterization of microsatellites from the canine genomeAnimal Genetics, 1993
- A Comprehensive Genetic Linkage Map of the Human GenomeScience, 1992
- A second-generation linkage map of the human genomeNature, 1992
- Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groupsGenomics, 1992
- Construction of a GT polymorphism map of human 9qGenomics, 1992
- Informativeness of human (dC-dA)n · (dG-dT)n polymorphismsGenomics, 1990
- Potential Z-DNA forming sequences are highly dispersed in the human genomeNature, 1982