Intellectual functioning in Duchenne muscular dystrophy: A review.

Publisher Website
Google Scholar
Abstract
Duchenne muscular dystrophy has traditionally been thought to be a primary disease of muscle, but recently it was suggested that it may be secondary to a neuronal defect or to a generalized disorder or protein synthesis and membrane. To date there is no proof to unequivocally support any of these theories. A higher incidence of mental retardation and decreased intellectual functioning was reported in the medical literature for Duchenne muscular dystrophy patients than for normals or other control groups. Recently there was strong evidence to suggest that verbal ability, as reflected by the Wechsler Intelligence Scale for Children Verbal scale IQ, may be more commonly and significantly impaired in Duchenne muscular dystropyy patients than is non-verbal ability, as reflected by the Performance scale IQ. A comprehensive review of intellectual functioning in Duchenne muscular dystropy was presented. To provide a basis for future attempts to relate the intellectual deficit in Duchenne muscular dystrophy to neuropsychological and neurobiological parameters of the disease.

This publication has 5 references indexed in Scilit: