The Binding Site of Ribosomal Protein L1 from Escherichia coli on the 23‐S Ribosomal RNA from Bacillus stearothermophilus

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Abstract
The region of B. stearothermophilus strain NCA 1503 23-S rRNA protected from T1 RNase digestion by the 50-S ribosomal subunit protein L1 from E. coli was established. The sequence of 115 nucleotides is compared to the analogous region in E. coli. The similar behavior of the RNA towards the recognition of protein L1 may be explained in terms of secondary base-pairing, even though there exists almost 40% difference between the primary nucleotide sequences.