COMPLEMENTARITY BETWEEN LAMBDA (λ) PHAGE AND ESCHERICHIA COLI
- 1 December 1963
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 50 (6) , 1177-1184
- https://doi.org/10.1073/pnas.50.6.1177
Abstract
From DNA-RNA hybrid studies, it was concluded that about 8 per cent of the [lambda] genome is complementary to the DNA of E. coli strains W3110 and B/5. At least 80 per cent of this homology lies outside of the [lambda] b2+ segment of the genome. There is no homology between [lambda] and Shigella dysenteriae, as defined experimentally. Various lines of evidence support the view that the observed homology is required for the formation of the lysogenic state rather than for trans-duction.Keywords
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