A Comparison of Cross Protection Between BCG, Hammondia hammondi, Besnoitia jellisoni and Toxoplasma gondii in Hamsters*

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Abstract
The effect of pretreatment with BCG strain of Mycobacterium tuberculosis or H. hammondi 21 days before challenge with lethal doses of T. gondii and B. jellisoni was studied in hamsters. The results indicated that the intracardial administration of BCG provided no protection against T. gondii or B. jellisoni. The hamsters immunized with H. hammondi survived challenge with 104 lethal doses of T. gondii but only 1 lethal dose with B. jellisoni, indicating strong cross protection between H. hammondi and T. gondii and only a marginal one between H. hammondi and B. jellisoni.