Calcification of Bruch's Membrane in Angioid Streaks With Homozygous Sickle Cell Disease
- 1 January 1987
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Ophthalmology (1950)
- Vol. 105 (1) , 93-98
- https://doi.org/10.1001/archopht.1987.01060010099039
Abstract
• Histochemical and light and electron microscopic studies of two eyes of a patient with homozygous sickle cell disease and angioid streaks demonstrated heavy calcification and breaks in Bruch's membrane. We were unable to demonstrate iron deposition by histochemical techniques or transmission electron microscopy. These studies suggest that calcification rather than iron deposition is the major factor leading to brittleness of Bruch's membrane in patients with hemolytic anemia and angioid streaks.This publication has 9 references indexed in Scilit:
- Angioid streaks in Jamaican patients with homozygous sickle cell disease.British Journal of Ophthalmology, 1981
- LASER TREATMENT OF CHOROIDAL NEOVASCULAR MEMBRANES IN ANGIOID STREAKSPublished by Wolters Kluwer Health ,1981
- Ocular findings of elderly cases of homozygous sickle-cell disease in Jamaica.British Journal of Ophthalmology, 1976
- Angioid Streaks in Sickle Cell Trait HemoglobinopathyAmerican Journal of Ophthalmology, 1974
- Elastic Tissue Degeneration in Sickle-Cell Disease* *From the Department of Ophthalmology and Research-Ophthalmology, Medical College of VirginiaAmerican Journal of Ophthalmology, 1960
- Angioid Streaks and Sickle-Cell Disease*American Journal of Ophthalmology, 1960
- ANGIOID STREAKSArchives of Ophthalmology (1950), 1941
- ANGIOID STREAKSArchives of Ophthalmology (1950), 1939