Clonidine in the treatment of mixed bipolar disorder
- 1 January 1989
- journal article
- research article
- Published by Wiley in Acta Psychiatrica Scandinavica
- Vol. 79 (1) , 108-110
- https://doi.org/10.1111/j.1600-0447.1989.tb09242.x
Abstract
In a mixed bipolar disorder patient, DST‐positive, treated with neuroleptics and antidepressants, the addition of clonidine (up to 0.6 mg/day) caused a rapid improvement in his psychopathology, without any significant side effects. The concentrations of the metabolites of noradrenaline, dopamine, and serotonin (MHPG, HVA, and 5‐HIAA), the hormone prolactin and the activity of dopamine‐beta‐hydroxylase estimated in plasma during the clonidine trial are also reported.Keywords
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