Acute megakaryoblastic leukaemia with 3q inversion and elevated thrombopoietin (TSF): an autocrine role for TSF?
- 1 December 1985
- journal article
- research article
- Published by Wiley in British Journal of Haematology
- Vol. 61 (4) , 687-694
- https://doi.org/10.1111/j.1365-2141.1985.tb02883.x
Abstract
Summary. A patient with acute megakaryoblastic leukaemia is described in whom exactly the same paracentric inversion of 3q was detected as in three previously documented cases. The patient's serum thrombopoietin (TSF) was significantly raised. Based on these findings we postulate a role for a gene (? oncogene) on chromosome 3q in thrombopoietin production. Abnormalities of 3q may assist in delineating a subgroup of acute nonlymphocytic leukaemia, namely acute megakaryoblastic leukaemia.This publication has 13 references indexed in Scilit:
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