Comparative efficacy of dry-cow treatment regimens against Staphylococcus aureus

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Abstract
Four dry-cow treatment regimens were evaluated against Staphylococcus aureus intramammary infections: 1) high persistency product at drying off and low persistency product 1 to 3 days prepartum; 2) high persistency product at drying oflF; 3) low persistency product 1 to 3 days prepartum; 4) untreated controls. Treatment 1 was no more effbzacious (64.4%) than Treatment 2 (61.3%). Both treatments were significantly different from spontaneous recovery observed in Treatment 4 (41.2%), but not significantly different from Treatment 3 (46.9%). Dry-cow therapy reduced new S. aureus intramammary infections during the dry period by half. Prepartum treatment eliminated more than 90% of new Streptococcus ubmis infections.