Immunohistochemical distribution of leucocyte antigens in lymphoid tissues of cynomolgus monkeys (Macaca fascicularis)
- 1 July 1993
- journal article
- research article
- Published by Wiley in Journal of Medical Primatology
- Vol. 22 (5) , 285-293
- https://doi.org/10.1111/j.1600-0684.1993.tb00673.x
Abstract
Crossreactivity of antibodies to human leucocyte antigens with lymphoid tissues of cynomolgus monkeys was studied by immunohistochemistry and immunoblotting. Of a total of 54 clusters of differentiation (CD) antigens, 39 were expressed essentially with the same immunostaining patterns in the monkey as in human lymphoid tissues. By immunoblotting L26 (CD20) detected a 35 Kd molecule in the monkey lymph node. Our observations indicated that most of the CD antigens are expressed and can be studied in lymphoid tissues of cynomolgus monkeys.Keywords
Funding Information
- Medicinska Forskningsrådet
- Cancerfonden
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