Death Due to Hepatic Necrosis in a Patient Receiving Zoxazolamine

Publisher Website
Google Scholar
Abstract
THE occurrence of fatal necrosis of the liver in 2 patients receiving zoxazolamine has been reported.1 Hepatic damage, as observed at post-mortem examination, could not definitely be attributed to drug toxicity, inasmuch as it did not differ from that occurring in viral hepatitis. Clinically, however, the likelihood of a viral infection was remote. Zoxazolamine had been given in doses of 250 mg. orally, three times daily, for one to two months. The case reported below is probably the third, and possibly the fourth,2 recorded case of the occurrence of massive hepatic necrosis in a patient receiving this drug§ in similar . . .