Chlamydial genital infection in Ibadan, Nigeria. A seroepidemiological survey.

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Abstract
Sera from patients attending a sexually transmitted diseases (STD) clinic, a family planning clinic and an antenatal clinic in Ibadan and from male blood donors from the same area were tested for the presence of type specific antichlamydial antibodies using a modified microoimmunofluorescence test. Among men and women attending the STD clinic, the exposure rates to Chlamydia trachomatis serotypes D-K (genital pathogens) were 18.7 and 26.7%, respectively. Antibody titers suggesting active disease in these men and women were found in 11.8 and 22.7%, respectively. The highest rate of exposure (35%) was among women attending the family planning clinic; of these women; 25% had antibody suggesting active disease. Titers of IgG antibody in this study were similar to those found among men and women with chlamydial genital infections in the UK. Antibodies to serotypes D-K were also detected in 10.3% of women attending an antenatal clinic and in 9.9% of male blood donors. The prevalence of antibodies to C. trachomatis serotypes A-C and lymphogranuloma venereum serotypes was low. Apparently, the prevalence of chlamydial genital infections in Ibadan among STD patients and especially those individuals not seeking treatment (family planning and antenatal clinic patients) is high. Since serious sequelae can follow chlamydial genital infections, it is imperative to carry out further investigations in this area.
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