Immediate renal imaging and renography with 99mTc methylene diphosphonate to assess renal blood flow, excretory function, and anatomy.

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Abstract
99mTc methylene diphosphonate (99mTc MDP) was evaluated as a clinical renal imaging agent in 20 patients referred for bone scintigraphy. Sequential scintigraphy started immediately after injection and yielded blood flow studies of high quality. Subsequent images accurately delineated renal anatomy and excretion in nonazotemic patients. Early images were vastly superior to delayed images in quality and demonstrated improved target-to-nontarget activity ratios (P < 0.001) and improved lesion detectability (P < 0.01). Renal imaging performed incidental to bone scintigraphy with MDP can be greatly enhanced by initiating sequential scintigraphy immediately after injection.

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