A position effect in the control of transcription at yeast mating type loci
- 22 January 1981
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 289 (5795) , 244-250
- https://doi.org/10.1038/289244a0
Abstract
The two mating type loci MATa and MATα each produce two mRNAs that are transcribed in opposite and diverging directions from central promoters. Silent copies of MATa (HMRa) and MATα (HMLα) contain identical DNA sequences throughout the transcribed region, yet are not transcribed. It is concluded that sequences to the left of HMRa (and probably HMLα) must somehow affect transcription initiated at the centre of each locus 700 to 1,400 base pairs away. A possible mechanism for this position effect is discussed.This publication has 19 references indexed in Scilit:
- Structure and organization of transposable of transposable mating type cassettes in Saccharomyces yeasts.Proceedings of the National Academy of Sciences, 1980
- The structure of transposable yeast mating type lociCell, 1980
- γ-β-Thalassaemia studies showing that deletion of the γ- and δ-genes influences β-globin gene expression in manNature, 1980
- MAR1—A REGULATOR OF THE HM a AND HMα LOCI IN SACCHAROMYCES CEREVISIAEGenetics, 1979
- Asymmetry and directionality in production of new cell types during clonal growth: the switching pattern of homothallic yeastCell, 1979
- Spliced early mRNAs of simian virus 40Proceedings of the National Academy of Sciences, 1978
- Conservative assembly and segregation of nucleosomal historiesCell, 1977
- Hybridization of RNA to double-stranded DNA: formation of R-loops.Proceedings of the National Academy of Sciences, 1976
- Restriction EndonucleaseCRC Critical Reviews in Biochemistry, 1976
- The Phenomenon of Position EffectPublished by Elsevier ,1950