Myotrophic and Androgenic Activities of Androstanazole. A New Heterocyclic Steroid

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Abstract
Myotrophic and androgenic activities of androstanazole (17[beta]-hydroxy-17[alpha]-methylandrostano [3,2-c] pyrazole) were evaluated using immature castrated male rats. The data indicate that androstan-azole is 1/7 as myotrophic and 1/33 as androgenic as testosterone pro-pionate when both agents are administered subcutaneously, whereas it is 2 times more myotrophic than, and 1/3 as androgenic as, methyl-testosterone when the 2 agents are given orally. The data show that androstanazole is relatively more anabolic than androgenic regardless of route of administration. The results are discussed in light of N retention data previously reported for this compound.

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