Microcell-mediated transfer of murine chromosomes into mouse, Chinese hamster, and human somatic cells.
- 1 January 1977
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 74 (1) , 319-323
- https://doi.org/10.1073/pnas.74.1.319
Abstract
The production and characterization of proliferating hybrid cell populations generated by fusion of murine microcells with intact mouse, Chinese hamster and human recipient cells was studied. The microcell hybrids so produced contained 1-5 intact murine chromosomes derived from the microcell donor. These transferred chromosomes were maintained as functioning genetic elements in the hybrid cells. Subnuclear particle-mediated chromosome trnasfer is a valid somatic cell genetic tool.This publication has 18 references indexed in Scilit:
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