Poor Clinical Sensitivity of Rapid Antigen Test for Influenza A Pandemic (H1N1) 2009 Virus
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Open Access
- 1 October 2009
- journal article
- research article
- Published by Centers for Disease Control and Prevention (CDC) in Emerging Infectious Diseases
- Vol. 15 (10) , 1662-1664
- https://doi.org/10.3201/eid1510.091186
Abstract
Influenza A pandemic (H1N1) 2009 virus RNA was detected by reverse transcription–PCR in 144 clinical samples from Bonn, Germany. A common rapid antigen–based test detected the virus in only 11.1% of these samples. The paramount feature of rapid test–positive samples was high virus concentration. Antigen-based rapid tests appear unsuitable for virologic diagnostics in the current pandemic.Keywords
This publication has 12 references indexed in Scilit:
- Rapid-Test Sensitivity for Novel Swine-Origin Influenza A (H1N1) Virus in HumansNew England Journal of Medicine, 2009
- Evaluation of multiple test methods for the detection of the novel 2009 influenza A (H1N1) during the New York City outbreakJournal of Clinical Virology, 2009
- Performance of influenza rapid point‐of‐care tests in the detection of swine lineage A(H1N1) influenza virusesInfluenza and Other Respiratory Viruses, 2009
- Low Sensitivity of Rapid Diagnostic Test for InfluenzaClinical Infectious Diseases, 2009
- Comparison of the performance of the rapid antigen detection actim Influenza A&B test and RT-PCR in different respiratory specimensJournal of Medical Microbiology, 2009
- A Novel Diagnostic Target in the Hepatitis C Virus GenomePLoS Medicine, 2009
- Real-time PCR compared to Binax NOW and cytospin-immunofluorescence for detection of influenza in hospitalized patientsJournal of Clinical Virology, 2008
- Performance of Binax NOW Flu A and B and direct fluorescent assay in comparison with a composite of viral culture or reverse transcription polymerase chain reaction for detection of influenza infection during the 2006 to 2007 seasonDiagnostic Microbiology and Infectious Disease, 2008
- Comparison of two rapid influenza A/B test kits with reference methods showing high specificity and sensitivity for influenza A infectionJournal of Medical Virology, 2006
- Simultaneous Detection of Influenza Viruses A and B Using Real-Time Quantitative PCRJournal of Clinical Microbiology, 2001