Contributions to the theory and practice of the chromatographic separation of enantiomers
Open Access
- 10 June 2005
- Vol. 17 (S1) , S205-S226
- https://doi.org/10.1002/chir.20133
Abstract
The theory and practice of enantioselective capillary chromatography employing metal coordination compounds and modified cyclodextrins as chiral stationary phases are treated. A unified approach involving all contemporary chromatographic methods and a single enantioselective column is described. Reliable thermodynamic data of enantioselectivity are derived by the retention-increment method. The existence of an isoenantioselective temperature is demonstrated. Kinetic enantiomerization studies are presented. The preparative-scale separation of enantiomers by gas chromatography with enantioselective packed columns is achieved. Unusual phenomena and future aspects of enantioselective chromatography are discussed. Chirality 17:S205–S226, 2005.Keywords
This publication has 107 references indexed in Scilit:
- Enantiomer Separations in Capillary Electrophoresis in the Case of Equal Binding Constants of the Enantiomers with a Chiral Selector: Commentary on the Feasibility of the ConceptAnalytical Chemistry, 2004
- Chiral separations using gas chromatographyTrAC Trends in Analytical Chemistry, 2002
- Self and nonself recognition of chiral catalysts: The origin of nonlinear effects in the amino‐alcohol catalyzed asymmetric addition of diorganozincs to aldehydesThe Chemical Record, 2001
- Electrokinetic chromatography: An interface between electrophoresis and chromatographyTrAC Trends in Analytical Chemistry, 1989
- Evidence for a Temperature Dependent Reversal of the Enantioselectivity in Complexation Gas Chromatography on Chiral PhasesAngewandte Chemie International Edition in English, 1989
- Temperature Dependent Inversion of Elution Sequence in the Resolution of α‐Amino Acid Enantiomers on Chiral Diamide SelectorsAngewandte Chemie International Edition in English, 1989
- Cytochrome P‐450‐catalyzed asymmetric epoxidation of simple prochiral and chiral aliphatic alkenes: species dependence and effect of enzyme induction on enantioselective oxirane formationChirality, 1989
- Chirodichroism of Different Enantiomeric Compositions of a Planar d8‐Metal ComplexAngewandte Chemie International Edition in English, 1981
- Determination of Equilibrium Constants of Silver-Olefin Complexes Using Gas ChromatographyJournal of the American Chemical Society, 1962
- Über die Spaltung der Tröger'schen Base in optische Antipoden, ein Beitrag zur Stereochemie des dreiwertigen StickstoffsHelvetica Chimica Acta, 1944