Halothane sensitivity and linkage of genes for H red blood cell antigens, phosphohexose isomerase (PHI) and 6‐phosphogluconate dehydrogenase (6‐PGD) variants in pigs*
- 24 April 1980
- journal article
- research article
- Published by Wiley in Animal Blood Groups and Biochemical Genetics
- Vol. 11 (2) , 93-107
- https://doi.org/10.1111/j.1365-2052.1980.tb01499.x
Abstract
Data from matings appropriate to test linkage in pigs of genes for halothane sensitivity (HAL), H red cell antigens, phosphohexose isomerase (PHI) and 6-phosphogluconate dehydrogenase (6-PGD) red cell isoenzyme variants were consistent with a gene order of Phi-Hal-H-Pgd. There was no unequivocal evidence for a Hal locus separate from Phi, although the phenotype of 1 pig not tested for halothane sensitivity suggested recombination between Hal and Phi. Breeding tests confirmed that in 2 cases there had been recombination between Hal and H. Offspring of 1 of these recombinant types provided evidence for a locus for a gene for inhibition of expression of A and O separate from the locus for H.Keywords
This publication has 14 references indexed in Scilit:
- Association between susceptibility to the malignant hyperthermia syndrome (MHS) and H blood types in Danish Landrace pigs explained by linkage disequilibriumLivestock Production Science, 1980
- Associative Additive Effects of Alleles of theHandPHILoci on the Quality of Meat from Danish Landrace PigsActa Agriculturae Scandinavica, 1979
- Further evidence for the existence of the [PHIA, HALn] haplotype in the Landrace breedAnimal Blood Groups and Biochemical Genetics, 1978
- Inheritance of reaction to halothane anaesthesia in pigsGenetics Research, 1977
- H Blood Types in Pigs as Predictors of Stress SusceptibilityScience, 1976
- Gene interaction and the A‐0 and H blood‐group systems in pigsAnimal Blood Groups and Biochemical Genetics, 1972
- Linear sequence of the autosomal loci PHI, H and 6‐PGD in pigs1Animal Blood Groups and Biochemical Genetics, 1971
- Close linkage between the locus for phosphohexose isomerase (PHI) and the H blood group locus in pigs1Animal Blood Groups and Biochemical Genetics, 1970
- Further Investigations on Linkage Between the Loci for Heme‐binding Globulins and K Blood Groups in Pigs1Vox Sanguinis, 1968
- Inherited variations in human phosphohexose isomeraseAnnals of Human Genetics, 1968