Induction of sister-chromatid exchanges by d(42 MeV)-Be neutrons in unstimulated human-blood lymphocytes
- 3 March 1988
- journal article
- research article
- Published by Oxford University Press (OUP) in The British Journal of Radiology
- Vol. 61 (723) , 231-234
- https://doi.org/10.1259/0007-1285-61-723-231
Abstract
The ability of d(42 Mev)-Be neutrons and 250 kV X rays to produce sister-chromatid exchanges (SCE) has been reexamined using unstimulated (G0) human-blood lymphocytes. Contrary to a previous report, the neutrons produced a significant and dose-dependent increase in SCE. X rays, as previously, produced no measurable increase at any absorbed dose. The relative biological effectiveness (RBE) for this end-point is therefore undefined and effectively infinite. In contrast to the findings of many workers, the between-cell distributions of SCE were, in most cases, underdispersed. This could imply that the SCE burden of a cell was not selectively neutral in these experiments.This publication has 11 references indexed in Scilit:
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