Selective Insulin Signaling through A and B Insulin Receptors Regulates Transcription of Insulin and Glucokinase Genes in Pancreatic β Cells
- 1 March 2001
- journal article
- research article
- Published by Elsevier in Molecular Cell
- Vol. 7 (3) , 559-570
- https://doi.org/10.1016/s1097-2765(01)00203-9
Abstract
No abstract availableKeywords
This publication has 42 references indexed in Scilit:
- Loss of Insulin Signaling in Hepatocytes Leads to Severe Insulin Resistance and Progressive Hepatic DysfunctionPublished by Elsevier ,2000
- Altered function of insulin receptor substrate-1–deficient mouse islets and cultured β-cell linesJournal of Clinical Investigation, 1999
- Branched-chain Amino Acids Are Essential in the Regulation of PHAS-I and p70 S6 Kinase by Pancreatic β-CellsJournal of Biological Chemistry, 1998
- Positive and negative regulatory elements are involved in transcriptional control of the rat glucokinase gene in the insulin producing cell line HIT M2.2.2FEBS Letters, 1994
- The Role of the Proximal CTAAT-Box of the Rat Glucokinase Upstream Promoter in Transcriptional Control in Insulin-Producing CellsBiological Chemistry Hoppe-Seyler, 1994
- Alternatively spliced variants of the insulin receptor protein. Expression in normal and diabetic human tissues.Journal of Clinical Investigation, 1992
- Distinct .alpha.-subunit structures of human insulin receptor A and B variants determine differences in tyrosine kinase activitiesBiochemistry, 1992
- The two isotypes of the human insulin receptor (HIR-A and HIR-B) follow different internalization kineticsBiochemical and Biophysical Research Communications, 1991
- Alternative splicing of human insulin receptor messenger RNABiochemical and Biophysical Research Communications, 1989
- Human insulin receptor and its relationship to the tyrosine kinase family of oncogenesNature, 1985