The Amino‐Acid Sequence of S‐100 Protein (PAP I‐b Protein) and Its Relation to the Calcium‐Binding Proteins
Open Access
- 1 September 1978
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 89 (2) , 379-388
- https://doi.org/10.1111/j.1432-1033.1978.tb12539.x
Abstract
The amino acid sequence of a brain‐specific protein, S‐100, has been determined by the analysis of four cyanogen bromide peptides and fourteen tryptic peptides derived from the protein. The protein chain consists of 91 amino acid residues and has a molecular weight of 10 507. The sequence shows regions of strong clustering of hydrophobic, basic and acidic amino acids, with an apparent calcium‐binding site in the acidic cluster.This publication has 48 references indexed in Scilit:
- Complete amino acid sequence of bacteriophage T4 internal protein I and its cleavage site on virus maturationJournal of Molecular Biology, 1977
- Primary structure of bacteriophage T4 internal protein II and characterization of the cleavage upon phage maturationJournal of Molecular Biology, 1976
- Refinement of the structure of carp muscle calcium-binding parvalbumin by model building and difference fourier analysisJournal of Molecular Biology, 1975
- Effect of a brain-specific protein (S-100 protein) on the nucleolar RNA polymerase activity in isolated brain nucleiCellular and Molecular Life Sciences, 1973
- The amino acid sequence of rabbit skeletal muscle troponin C: Gene replication and homology with calcium ‐binding proteins from carp and hake muscleFEBS Letters, 1973
- Effect of two brain specific proteins (S100 and 14.3.2) on cation diffusion across artificial lipid membranesBiochemical and Biophysical Research Communications, 1971
- Correlation of the S100 brain protein with behaviorExperimental Cell Research, 1970
- The Diagram, a Method for Comparing SequencesEuropean Journal of Biochemistry, 1970
- A STUDY OF SPECIFIC BRAIN PROTEINS ON THE SEMI‐MICRO SCALEJournal of Neurochemistry, 1966
- A soluble protein characteristic of the nervous systemBiochemical and Biophysical Research Communications, 1965