Proliferative activity of myocardial capillary wall cells in dipyridamole-treated rats
- 1 November 1978
- journal article
- research article
- Published by Oxford University Press (OUP) in Cardiovascular Research
- Vol. 12 (11) , 692-695
- https://doi.org/10.1093/cvr/12.11.692
Abstract
The hearts of rats treated with dipyridamole were studied by light microscope autoradiography and measurement of tissue radioactivity after intravenous injection of 3H-thymidine. Total tissue radioactivity was significantly increased in the hearts of the dipyridamole-treated animals. Only capillary wall cells were labelled in the autoradiograms. The observations indicate a proliferation of capillary wall cells, suggesting a neoformation of myocardial capillaries during dipyridamole treatment.Keywords
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