Activity of some naphthoquinones on blood stream forms of Trypanosoma cruzi
- 1 July 1987
- journal article
- research article
- Published by Oxford University Press (OUP) in Transactions of the Royal Society of Tropical Medicine and Hygiene
- Vol. 81 (4) , 609-610
- https://doi.org/10.1016/0035-9203(87)90427-5
Abstract
Accidental transmission of Chagas disease to man by blood transfusion is a serious problem in Latin America. This paper describes the testing of several naphthoquinones, some of which were active against blood trypomastigotes in vitro at 4 degrees C and might therefore warrant further study for preventing transmission of Chagas disease by blood transfusion.Keywords
This publication has 8 references indexed in Scilit:
- A novel series of chemical structures active in vitro against the trypomastigote form of Trypanosoma cruziTransactions of the Royal Society of Tropical Medicine and Hygiene, 1984
- Prevention of Transfusion-Induced Chagas' Disease by Amphotericin B *The American Journal of Tropical Medicine and Hygiene, 1980
- Evaluation of the toxicity of 3-allyl-β-lapachone against Trypanosma cruzi bloodstream formsMolecular and Biochemical Parasitology, 1980
- Present status of chemotheraphy and chemoprophylaxis of human trypanosomiasis in the Western HemispherePharmacology & Therapeutics, 1979
- In vitroandin vivoevaluation of the toxicity of 1,4-naphthoquinone and 1,2-naphthoquinone derivatives againstTrypanosoma cruziPathogens and Global Health, 1978
- Schistosomiasis mansoni: blockage of cercarial skin penetration by chemical agents: I. naphthoquinones and derivativesTransactions of the Royal Society of Tropical Medicine and Hygiene, 1977
- LVII.—The constitution of “lapachic acid”(lapachol) and its derivativesJournal of the Chemical Society, Transactions, 1892