ASSESSMENT OF ACYCLOVIR ON ACUTE OCULAR INFECTION INDUCED BY DRUG-RESISTANT STRAINS OF HSV-1
- 1 January 1981
- journal article
- research article
- Vol. 20 (2) , 230-235
Abstract
Effects of topical acyclovir treatment on rabbit eyes infected with parent McKrae, idoxuridine-resistant and vidarabine-resistant strains of HSV-1 [herpes simplex virus type 1] were studied. Topical acyclovir therapy given 4 times a day was significantly more effective than idoxuridine and vidarabine at suppressing acute herpetic ocular disease induced by either sensitive or drug-resistant strains of HSV-1. Virus isolation from neural tissues indicated that none of the therapy prevented viral infection of the nervous system.This publication has 6 references indexed in Scilit:
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