Quantitation of pterosins A and B, and ptaquiloside, the main carcinogen of pteridium aquilinum (L. Kuhn), by high pressure liquid chromatography
- 1 July 1992
- journal article
- research article
- Published by Wiley in Phytochemical Analysis
- Vol. 3 (4) , 160-164
- https://doi.org/10.1002/pca.2800030404
Abstract
A quantitative method for the assessment of ptaquiloside and pterosins A and B in bracken fern has been developed. The technique involves quantitative extraction of fresh plant tissue, base‐induced decomposition of ptaquiloside to pterosin B, followed by prepurification of products on a silica gel microcolumn and quantitative high pressure liquid chromatography. The method has been used to estimate the contents of these norsequiter‐penes in fronds and rhizomes of Pteridium aquilinum var. caudatum from northern South America.Keywords
This publication has 20 references indexed in Scilit:
- Chemical assay of ptaquiloside, the carcinogen of pteridium aquilinum, and the distribution of related compounds in the pteridaceaePhytochemistry, 1989
- Modification and cleavage of DNA by ptaquiloside. A new potent carcinogen isolated from bracken fernJournal of the Chemical Society, Chemical Communications, 1989
- Assay of ptaquiloside, the carcinogenic principle of bracken, Pteridium aquilinum, by mutagenicity testing in Salmonella typhimuriumMutagenesis, 1986
- Separation of Diterpenoid Alkaloid Mixtures Using Vacuum Liquid ChromatographyJournal of Natural Products, 1986
- Carcinogenic Principles Isolated from Bracken FernCRC Critical Reviews in Toxicology, 1986
- Hyperplastic nodules of the liver induced in rats fed bracken dietCancer Letters, 1984
- Synthesis of α‐carboxy‐γ‐butyrolactones by rearrangement of capto‐dative cyclopropanes on silica surfacesJournal of Heterocyclic Chemistry, 1982
- Bracken thiaminase-mediated neurotoxic syndromesBotanical Journal of the Linnean Society, 1976
- Fern Foods of Japan and the Problem of ToxicityAmerican Fern Journal, 1973
- 1-Indanone Derivatives from Bracken, Pteridium aquilinum var. latiusculumCHEMICAL & PHARMACEUTICAL BULLETIN, 1971