Induction of Liver Tumors in the Syrian Golden Hamster by Feeding Dimethylnitrosamine2

Abstract
The chronic administration of dimethylnitrosamine in the drinking water to Syrian golden hamsters resulted in a high incidence of both liver-cell carcinomas and cholangiocarcinomas. Two hemangioendotheliomas of the liver and 1 adenoma of the kidney were also observed. No tracheal or lung tumors were recorded.