Plateletpheresis Using the Haemonetics Model 30 Cell Separator

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Abstract
Plateletpheresis [in humans] using the Haemonetics Model 30 cell separator results in a mean collection of 5.5 .times. 1011 platelets. This product contains substantial numbers of erythrocytes and mononuclear cells which can be effectively removed by centrifugation but with a 23% loss of platelets as well. The mean decrement in donor''s platelet count during the procedure, which is 78,000/mm3, is not commensurate with the number of platelets collected suggesting donor platelet mobilization. Platelets collected by this technique, when transfused into unselected recipients, give platelet increments comparable to platelets produced in the standard batch manner.