Abstract
A case of acute idiopathic porphyria is presented with spinal fluid abnormalities. There are no reported instances of such changes of the spinal fluid in cases with neurological findings. It is postulated that these changes were due to the abnormal porphyrins affecting the meninges. However an infectious virus disease producing a secondary porphyria or activating a "latent" porphyria may have been a factor. The importance of this finding in differential diagnosis is emphasized.

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