Covalent binding of acetaminophen to mouse hemoglobin. Identification of major and minor adducts formed in vivo and implications for the nature of the arylating metabolites

This publication has 30 references indexed in Scilit:

• The use of alkoxycarbonyl derivatives for the mass spectral analysis of drug-thioether metabolites. Studies with the cysteine, mercapturic acid and glutathione conjugates of acetaminophen
  Journal of Mass Spectrometry, 1988
• Identification of S-(2,5-dihydroxyphenyl)-cysteine and S-(2,5-dihydroxyphenyl)-N-acetyl-cysteine as urinary metabolites of acetaminophen in the mouse. Evidence for p-benzoquinone as a reactive intermediate in acetaminophen metabolism
  Chemico-Biological Interactions, 1988
• Structural characterization of the major covalent adduct formed in vitro between acetaminophen and bovine serum albumin
  Chemico-Biological Interactions, 1985
• The covalent binding of acetaminophen to protein. Evidence for cysteine residues as major sites of arylation in vitro
  Chemico-Biological Interactions, 1984
• Conversion of the prosthetic moieties of glutathione pathway conjugates to the correspondingS- acetates
  Journal of Mass Spectrometry, 1982
• Covalent Binding of Reactive Intermediates to Hemoglobin as an Approach for Determining the Metabolic Activation of Chemicals – Ethylene: Removal of Environmental Chemicals from the Body
  Drug Metabolism Reviews, 1982
• Renal necrosis, glutathione depletion, and covalent binding after acetaminophen
  Toxicology and Applied Pharmacology, 1978
• Evaluation of genetic risks of alkylating agents. II. Haemoglobin as a dose monitor
  Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1976
• PLASMA-PARACETAMOL HALF-LIFE AND HEPATIC NECROSIS IN PATIENTS WITH PARACETAMOL OVERDOSAGE
  The Lancet, 1971
• LIVER NECROSIS FROM PARACETAMOL
  British Journal of Pharmacology and Chemotherapy, 1966