Reduction of bovine pulmonary hypertension by normoxia, verapamil and hexaprenaline
- 1 September 1977
- journal article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 33 (9) , 1192-1194
- https://doi.org/10.1007/bf01922322
Abstract
In calves with hypoxic pulmonary hypertension, resistance was reduced by 40±3% with normoxia, 19±4% with verapamil, and 60±1% with hexoprenaline. It is possible that the increased resistance during normoxia is due partly to vasoconstriction rather than solely to vascular thickening, and that the vasoconstriction is due to an abnormality in calcium metabolism by the hypertensive vasculature.Keywords
This publication has 26 references indexed in Scilit:
- The genetic factor influencing pulmonary hypertension in cattle at high altitudeCardiovascular Research, 1974
- The effect of verapamil on the response to noradrenaline or to potassium-depolarization in isolated vascular stripsMicrovascular Research, 1974
- Vascular Smooth Muscle UpdatedCirculation Research, 1973
- Beeinflussung der Betareceptoren im kleinen Kreislauf und Bronchialsystem durch die HypoxieLung, 1972
- Bradycardia, increased cardiac output, and reversal of pulmonary hypertension in altitude natives living at sea level.Heart, 1971
- Pulmonary and systemic circulatory effects and β-adrenergic selectivity of hexoprenaline, salbutamol, oxyfedrine, and isoproterenolEuropean Journal of Pharmacology, 1971
- Hypertensive pulmonary vascular disease in states of chronic hypoxiaThe Journal of Pathology and Bacteriology, 1968
- Chronic pharmacologic treatment of experimental hypoxic pulmonary hypertension: With observations on rate of change in pulmonary arterial pressureAmerican Heart Journal, 1966
- High Altitude-Induced Pulmonary Hypertension in Normal CattleCirculation Research, 1962
- The Problem of Medial Hypertrophy in Pulmonary HypertensionRespiration, 1962