Comparison of adult height between patients with XX and XY gonadal dysgenesis: support for a Y specific growth gene(s).
Open Access
- 1 August 1992
- journal article
- research article
- Published by BMJ in Journal of Medical Genetics
- Vol. 29 (8) , 539-541
- https://doi.org/10.1136/jmg.29.8.539
Abstract
Adult height was compared between published cases of patients with XX gonadal dysgenesis (XXGD) and those with XY gonadal dysgenesis (XYGD). The mean adult height of XYGD patients (171.0 cm (SD 7.8), n = 27) was significantly greater than that of XXGD patients (164.4 cm (7.7), n = 27) (p less than 0.01). This finding supports the existence of a Y specific growth gene(s) which promotes statural growth independently of the effects of gonadal sex steroids.Keywords
This publication has 52 references indexed in Scilit:
- A deletion map of the human Yq11 region: Implications for the evolution of the Y chromosome and tentative mapping of a locus involved in spermatogenesisGenomics, 1991
- Pubertal growth in patients with androgen insensitivity: Indirect evidence for the importance of estrogens in pubertal growth of girlsThe Journal of Pediatrics, 1986
- Clinical longitudinal standards for height and height velocity for North American childrenThe Journal of Pediatrics, 1985
- Yq deletion with short stature, abnormal male development, and schizoid character disorder.Journal of Medical Genetics, 1983
- Pure XX gonadal dysgenesis in identical twinsClinical Genetics, 1982
- Tooth sizes in two males with deletions of the long arm of the Y‐chromosomeAnnals of Human Genetics, 1981
- Growth in children with 45,Xo Turner's syndromeArchives of Disease in Childhood, 1974
- Deletion of the long arms of the Y chromosome with normal male development and intelligenceJournal of Medical Genetics, 1974
- Males with an XYY sex chromosome complement.Journal of Medical Genetics, 1968
- CYTOGENETIC STUDIES IN PRIMARY AMENORRH$OElig;AThe Lancet, 1961