Oncogenic Ras Represses Transforming Growth Factor-β/Smad Signaling by Degrading Tumor Suppressor Smad4
Open Access
- 1 August 2001
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 276 (31) , 29531-29537
- https://doi.org/10.1074/jbc.m100069200
Abstract
No abstract availableKeywords
This publication has 26 references indexed in Scilit:
- Higher frequency of Smad4 gene mutation in human colorectal cancer with distant metastasisOncogene, 1999
- A mechanism of repression of TGFbeta / Smad signaling by oncogenic RasGenes & Development, 1999
- Smad3 Mutant Mice Develop Metastatic Colorectal CancerCell, 1998
- TGF-β singaling and cancer: structural and functional consequences of mutations in SmadsMolecular Medicine Today, 1998
- TGF-β SIGNAL TRANSDUCTIONAnnual Review of Biochemistry, 1998
- Mutations in the SMAD4/DPC4 Gene in Juvenile PolyposisScience, 1998
- Intestinal Tumorigenesis in Compound Mutant Mice of both Dpc4(Smad4) and Apc GenesCell, 1998
- Lessons from Hereditary Colorectal CancerCell, 1996
- MADR2 Maps to 18q21 and Encodes a TGFβ–Regulated MAD–Related Protein That Is Functionally Mutated in Colorectal CarcinomaCell, 1996
- DPC4 , A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1Science, 1996