The Carbohydrates in Normal and Abnormal Cerebrospinal Fluid

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Abstract
The Somogyi method gave lower results than the Hagedorn-Jensen method in cerebrospinal fluid sugar estimations of both "normals" and meningitic cases. Paper chromatography showed that there were at least 3 reducing substances (glucose, fructose, glucosamine) in the cerebrospinal fluid of normal people and non-meningitic cases. There were also yet-unidentified substances with reducing action on Hagedorn-Jensen and Somogyi reagents. A fall in fructose values seemed helpful in the diagnosis of tuberculous meningitis. Hexosamine values in meningeal disease did not differ significantly from its normal value.