IgM-induced tumor cell cytotoxicity mediated by normal thymocytes.

Open Access

1 August 1975

journal article
Published by Rockefeller University Press in The Journal of Experimental Medicine

Vol. 142 (2) , 542-547
https://doi.org/10.1084/jem.142.2.542

Abstract

In summary, we have found that IgM, from mice which have undergone regression of primary MSV tumors, will induce cytotoxicity against the appropriate target cells by normal splenocytes and normal thymocytes. The thymocyte-induced cytotoxicity i

Keywords

This publication has 19 references indexed in Scilit:

In Vitro Demonstration of Complement-Dependent Cytotoxic Antibodies to Moloney Sarcoma Cells
The Journal of Immunology, 1974
The immune response to primary moloney sarcoma virus tumors in BALB/C mice: Cellular and humoral activity of long-term regressors
International Journal of Cancer, 1974
The humoral antibody response to a primary viral neoplasm (MSV) through its entire course in BALB/c mice
International Journal of Cancer, 1973
Antitumour Activity in vitro Dependent on Immune B Lymphocytes
Nature New Biology, 1973
Cell-mediated immune reaction against tumors induced by oncornaviruses. II. Nature of the effector cells in tumor-cell cytolysis
International Journal of Cancer, 1973
The lymphocyte response to a primary viral neoplasm (MSV) through its entire course in BALB/c mice
International Journal of Cancer, 1972
IN VITRO CYTOTOXICITY BY A NONTHYMUS-PROCESSED LYMPHOCYTE POPULATION WITH SPECIFICITY FOR A VIRALLY DETERMINED TUMOR CELL SURFACE ANTIGEN
The Journal of Experimental Medicine, 1972
Cytotoxic Lymphocytes from Rats depleted of Thymus Processed Cells
Nature New Biology, 1971
Antibody‐induced destruction of colon antigen‐coated chicken erythrocytes by normal human lymphocytes
European Journal of Immunology, 1971
The role of immunoglobulins in lymphocyte-mediated cell damage, in vitro. I. Comparison of the effects of target cell specific antibody and normal serum factors on cellular damage by immune and non-immune lymphocytes.
1970