DEZOCINE FOR POSTOPERATIVE WOUND PAIN

  • 1 January 1984
    • journal article
    • research article
    • Vol. 22  (9) , 502-505
Abstract
An assessment was made of the analgesic effectiveness of a single i.m. injection of dezocine, 10 mg or 15 mg; morphine, 10 mg; or a placebo, in 160 patients with moderate to severe postoperative pain. Dezocine, 10 mg, was as effective as, and had approximately the same duration of action as, morphine, 10 mg. Dezocine, 15 mg, was more effective than 10 mg of either dezocine or morphine, as assessed by 3 efficacy scales (verbal and analog pain intensity and pain relief); both drugs were significantly (P < 0.05) more effective than the placebo, as assessed by the 3 efficacy scales and the overall evaluation of the investigator. A small percentage of patients suffered nausea and became sedated; the drugs and placebo did not differ statistically with respect to the side effects. Blood pressure, heart rate and respiratory rate generally were slightly decreased by both drugs.