Heparin Resistance (Measured by the Heparin Thrombin Time) and Plasma Fibrinogen in Various Diseases

Publisher Website
Google Scholar
Abstract
The heparin thrombin time was investigated in 144 patients. In 27 (73%) out of 37 patients with malignant tumours or thrombo-embolic diseases it was shortened. Out of the remaining 107 patients suffering from other diseases, including 40 with arteriosclerotic heart disease and/or other arteriosclerosis without thromboembolic complications, 26(24%) had a shortened heparin thrombin time. In 70 patients plasma fibrinogen was determined simultaneously. This revealed a certain correlation between the increase of fibrinogen and the shortening of the heparin thrombin time. However, there were divergences, both in the form of a greatly shortened heparin thrombin time coexisting with a normal fibrinogen and in the form of a normal heparin thrombin time coexisting with a highly increased fibrinogen.

This publication has 5 references indexed in Scilit: