Genetic Association of the Antiviral Restriction Factor TRIM5α with Human Immunodeficiency Virus Type 1 Infection
Open Access
- 1 March 2006
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 80 (5) , 2463-71
- https://doi.org/10.1128/jvi.80.5.2463-2471.2006
Abstract
The innate antiviral factor TRIM5α restricts the replication of some retroviruses through its interaction with the viral capsid protein, leading to abortive infection. While overexpression...Keywords
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