Acquired amegakaryocytic thrombocytopaenia in a child
- 1 June 1992
- journal article
- case report
- Published by Wiley in Journal of Paediatrics and Child Health
- Vol. 28 (3) , 263-266
- https://doi.org/10.1111/j.1440-1754.1992.tb02660.x
Abstract
A boy aged 5 years is described with amegakaryocytic thrombocytopaenia, which was associated with defective granulopoiesis and erythropoiesis, but did not evolve into marrow aplasia. Marrow cultures confirmed the presence of abnormalities in each of the haemopoietic lineages and identified defective maturation of megakaryocytic precursors. The was no evidence of a humoral inhibitor of megakaryopoiesis. The patient's blood cell counts responded to treatment with oxymetholone.Keywords
This publication has 13 references indexed in Scilit:
- Congenital Amegakaryocytic ThrombocytopeniaJournal of Pediatric Hematology/Oncology, 1990
- Human recombinant erythropoietin promotes differentiation of murine megakaryocytes in vitro.Journal of Clinical Investigation, 1987
- Amegakaryocytic thrombocytopeniaAmerican Journal of Hematology, 1985
- An Antibody Cytotoxic to Megakaryocyte Progenitor Cells in a Patient with Immune Thrombocytopenic PurpuraNew England Journal of Medicine, 1985
- Acquired amegakaryocytic thrombocytopenic purpura: a syndrome of diverse etiologiesBlood, 1982
- Proposals for the classification of the myelodysplastic syndromesBritish Journal of Haematology, 1982
- Immature megakaryocytes in the mouse: physical characteristics, cell cycle status, and in vitro responsiveness to thrombopoietic stimulatory factorBlood, 1982
- Thrombocytopenia with Decreased MegakaryocytesAnnals of Internal Medicine, 1981
- Acquired hypomegakaryocytic thrombocytopenic purpura. Occurrence in a patient with absent thrombopoietic stimulating factorArchives of internal medicine (1960), 1980
- THROMBOCYTOPENIA WITH ABSENT RADIUS (TAR)Medicine, 1969